Oncotype DX® tools for Genomic Education

Oncotype DX tools is an educational website that has two calculator tools to help physicians understand how hormonal therapy and pathologic and clinical factors can be assessed in conjunction with the Oncotype DX Breast Recurrence Score™ result to evaluate a patient’s risk of distant recurrence (prognosis).

Oncotype DX User Tools
Oncotype DX Tools User Guide

 


RSPC (Recurrence Score-Pathology-Clinical) Calculator

RSPC may help physicians understand how integrating clinical and pathological factors with the Breast Recurrence Score result can enhance the understanding of the score.

  • Input:
    • Oncotype DX Breast Recurrence Score
    • Patient age
    • Tumor size
    • Tumor grade
    • Planned adjuvant hormonal therapy (tamoxifen or aromatase inhibitor)
  • Output:
    • Integrated assessment of the risk of distant recurrence for node negative, ER positive invasive disease
    • Option to produce a numerical or a graphical printout

 



Christy Russell, MD, Associate Professor of Clinical Medicine, Director of USC Norris Lee Breast Center


Breast Recurrence Score & Hormonal Treatment Calculator

This calculator allows input of an Oncotype DX Breast Recurrence Score result to view estimates of the risk of distant recurrence depending on which adjuvant hormonal therapy is planned (tamoxifen or an aromatase inhibitor).

  • Input:
    • Oncotype DX Breast Recurrence Score
    • Planned adjuvant hormonal therapy (tamoxifen or aromatase inhibitor)
  • Output:
    • Risk of distant recurrence for node negative, ER positive invasive disease
    • Option to produce a numerical or a graphical printout

The two calculators are based on clinical experience in newly diagnosed female patients with lymph node–negative, ER-positive invasive breast cancer. The applicability of these calculator tools to patients with different characteristics (lymph node–positive, ER-negative, male, or not newly diagnosed) is not known.

The information and calculators included in the Oncotype DX tools site are for educational purposes only, and are not intended to render medical advice or to facilitate the diagnosis or treatment of patients with breast cancer. The information derived from the calculators presented on the Oncotype DX tools site has not been validated under the Clinical Laboratory Improvement Amendments (CLIA) for use in determining the prognosis of patients with breast cancer or the magnitude of benefit that may be predicted from treatments for breast cancer. The information derived from the calculators presented on this educational site is not intended to replace or substitute or be considered an add-on or separate diagnostic test from the Oncotype DX Breast Recurrence Score for the management of patients with breast cancer.

The Oncotype DX tools educational website is accessed through the convenient online Genomic Health® physician portal.  In addition to the Oncotype DX tools, additional advantages of the portal include:

  • Orders may be viewed online, printed, or downloaded (as PDFs).
  • All patient orders and reports can be viewed, tracked, and sorted quickly and efficiently.
  • Virtually eliminates the need for follow-up calls if information is missing.

To register for the physician portal, please contact Customer Service: 

 

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